Manitoba Nephrology Nurse Practice Test

Which of the following is a common complication of CKD?

1. Severe hyperglycemia

2. Metabolic acidosis

3. Neuropathic pain

4. Skin infections

The correct answer is: Metabolic acidosis

Chronic kidney disease (CKD) is associated with various metabolic imbalances due to the kidneys' diminished ability to excrete waste products and regulate biochemical processes. One significant complication that arises in patients with CKD is metabolic acidosis. In CKD, the kidney's capacity to excrete hydrogen ions and produce bicarbonate is impaired. As a result, there is an accumulation of acids in the body, which leads to a decrease in blood pH, manifesting as metabolic acidosis. This condition can have various systemic effects, including altering the functioning of the cardiovascular and respiratory systems, as well as impacting bone health and muscle function. Addressing metabolic acidosis is crucial, as it can worsen the progression of kidney disease and lead to other complications such as muscle wasting and increased cardiovascular risk. Understanding metabolic acidosis as a common complication emphasizes the importance of regular monitoring and management of acid-base status in patients with CKD. Management strategies may include dietary adjustments, pharmacologic interventions, or dialysis in more advanced cases.