Manitoba Nephrology Nurse Practice Test

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What portion of the glomerular filtrate is reabsorbed by the proximal convoluted tubule?

  1. 1/3

  2. 2/3

  3. 3/4

  4. All

The correct answer is: 2/3

The proximal convoluted tubule (PCT) is responsible for the reabsorption of approximately 65-70% of glomerular filtrate, which aligns closely with the choice indicating that about two-thirds of the filtrate is reabsorbed. This high efficiency in reabsorption is vital for maintaining fluid and electrolyte balance in the body. During this process, the PCT reabsorbs essential substances such as glucose, amino acids, bicarbonate, sodium, and water, which are critical for bodily functions. The specialized epithelial cells of the PCT have numerous microvilli, enhancing the surface area for absorption, and are equipped with various transporters and channels to facilitate this process. Other portions of the nephron contribute to the reabsorption of filtrate, but the PCT is the primary site for initial and substantial reabsorption, making the choice of two-thirds a fitting representation of the proportion of filtrate reabsorbed in this segment.

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