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What is a primary goal in treating pre-renal AKI?

  1. To eliminate all potential sources of infection

  2. To replace lost kidney function

  3. To restore renal perfusion

  4. To start dialysis immediately

The correct answer is: To restore renal perfusion

The primary goal in treating pre-renal acute kidney injury (AKI) is to restore renal perfusion. Pre-renal AKI is typically caused by factors that reduce blood flow to the kidneys, leading to decreased glomerular filtration rate (GFR). By improving renal perfusion, you can enhance blood flow to the kidneys, which in turn can help to reverse the injury and restore normal kidney function. Restoring perfusion might involve addressing underlying issues such as dehydration, heart failure, or any other conditions that impair blood flow. Interventions can include administering fluids, adjusting medication dosages, or managing blood pressure effectively. Focusing on restoring renal perfusion helps to prevent further kidney damage and promotes recovery. While addressing infection or considering dialysis may be important in other contexts or types of kidney injury, they are not primary concerns in the management of pre-renal AKI specifically. The focus for pre-renal conditions is primarily on correcting the factors that affect blood flow to the kidneys. Hence, prioritizing the restoration of renal perfusion aligns with the clinical approach to managing this type of acute kidney injury.