Manitoba Nephrology Nurse Practice Test

Decreased kidney function is a key sign of nephrotoxic medication effects because these types of drugs can cause direct injury to the kidney tissues. The kidneys are responsible for filtering waste and excess fluid from the bloodstream, and when they are damaged or impaired, their ability to perform these functions diminishes. This can be observed through various indicators such as elevated serum creatinine levels or decreased glomerular filtration rate (GFR), signaling that the kidney's function is not optimal. Monitoring kidney function is crucial when patients are on medications known for their nephrotoxic potential, as timely detection of decreased function allows for interventions to prevent further damage.