Manitoba Nephrology Nurse Practice Test

Hypertension is a common complication associated with Autosomal Dominant Polycystic Kidney Disease (ADPKD) due to several mechanisms. One significant aspect is the impact of renal cysts on kidney function, which can alter the structure and function of the blood vessels within the kidneys, leading to increased blood pressure. Additionally, the disease process may result in an increase in renin production, a hormone that plays a critical role in regulating blood pressure. Elevated renin levels can lead to the activation of the renin-angiotensin-aldosterone system, further contributing to hypertension.

In patients with ADPKD, hypertension is often present even before the onset of noticeable kidney dysfunction, making it an important aspect of monitoring and management in these patients. Effective control of blood pressure is crucial as it not only reduces the risk of cardiovascular events but may also help slow the progression of kidney disease. Regular screening for hypertension is, therefore, an essential component of care for individuals with ADPKD.